IL1A 蛋白
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北京 101111
Quick Overview for IL1A 蛋白 (ABIN935582)
抗原
See all IL1A 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS
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产品特性
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Purified recombinant Human IL1 alpha protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of Mouse D10S cells is 2 x 10^8 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL1 alpha
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背景
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IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells.
Alternative Names: Leukocyte Endogenous Mediator protein, Lymphocyte-activating factor protein, IL-1 protein, Interleukin 1 alpha protein, MCF protein, Mononuclear Cell Factor protein, IL 1 protein, IL1, IL-1 alpha protein, EP protein, LEM protein, Endogenous Pyrogen protein, Hematopoietin-1 protein, LAF protein, IL-1, IL 1 -
分子量
- 17.7 kDa
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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