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Interferon gamma Protein (IFNG)

This Recombinant Interferon gamma protein is expressed in 大肠杆菌(E. Coli) and has been mentioned in 1 publication.
产品编号 ABIN935524
发货至: 中国
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Quick Overview for Interferon gamma Protein (IFNG) (ABIN935524)

抗原

See all Interferon gamma (IFNG) 蛋白
Interferon gamma (IFNG)

蛋白类型

Recombinant

生物活性

Active

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大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    MQGTLIESLE SLKNYFNSSS MDAMEGKSLL LDIWRNWQKD GNTKILESQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT NFFSNSKAKK DAFMSIAKFE VNNPQIQHKA VNELIRVIHQ LSPESSLRKR KRSRC

    产品特性

    Purified recombinant Human IFN gamma protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by a cytopathic affect inhibition assay with Mouse L929 cells challenged with EMC virus was 1 x 10^7 units/mg.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 10 mM Na0 O4 pH7.2 to a concentration of 0.1-1.0 mg/mL. When dissolved, dilute further into aqueous buffered solutions.

    缓冲液

    Lyophilized from 10 mM Na3PO4, pH7.2.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • POGO, BRAWERMAN, CHARGAFF: "New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis." in: Biochemistry, Vol. 1, pp. 128-31 (PubMed).

  • 抗原

    Interferon gamma (IFNG)

    别名

    IFN gamma

    背景

    IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells.
    Alternative Names: IFN g protein, Immune Interferon protein, T cell interferon protein, IFN-g protein, MAF protein, type II interferon protein, Interferon gamma protein

    分子量

    15.6 kDa

    途径

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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