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Interferon gamma Protein (IFNG)

IFNG 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % pure Active
产品编号 ABIN935522
发货至: 中国
  • 抗原 See all Interferon gamma (IFNG) 蛋白
    Interferon gamma (IFNG)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
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    资源
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    大肠杆菌(E. Coli)
    序列
    MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ
    产品特性
    Purified recombinant Human IFN gamma protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 5.0-10.0 ng/mL.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per μg (1 EU/μg).
    Top Product
    Discover our top product IFNG 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in water to a concentration of 1.0 mg/mL.
    缓冲液
    Lyophilized from 10 mM NaPO4, pH 7.4.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    RT/-20 °C
  • 抗原
    Interferon gamma (IFNG)
    别名
    IFN gamma (IFNG 产品)
    背景
    IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells.
    Alternative Names: IFN-g protein, T cell interferon protein, type II interferon protein, IFN g protein, Immune Interferon protein, MAF protein, Interferon gamma protein
    分子量
    16.7 kDa
    途径
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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