IL1A 蛋白
Quick Overview for IL1A 蛋白 (ABIN935485)
抗原
See all IL1A 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
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产品特性
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Purified recombinant Human IL1 alpha protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of Mouse D10S cells is ? 0.001 ng/mL, corresponding to a specific activity of ? 1 x 10^9 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 1 alpha (IL1A) (Active) protein
IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) proteinIL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) protein (Fc Tag)IL1A 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1 alpha (IL1A) (AA 115-270) protein (His tag)IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 alpha (IL1A) proteinIL1A 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) (AA 1-271) protein (GST tag)IL1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) (AA 172-271) protein (GST tag)IL1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) proteinIL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90% by SDS-PAGE SDS
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- Lyophilized from 10 mM tris, pH 8.0, with 50 mM NaCl.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL1 alpha
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背景
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IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.
Alternative Names: Interleukin 1 alpha protein, Leukocyte Endogenous Mediator protein, MCF protein, EP protein, LAF protein, Hematopoietin-1 protein, Lymphocyte-activating factor protein, IL-1, IL1, IL-1 alpha protein, Mononuclear Cell Factor protein, Endogenous Pyrogen protein, IL 1 protein, LEM protein, IL 1, IL-1 protein -
分子量
- 18 kDa
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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