IL1A 蛋白
Our Local Distributor
北京 101111
Quick Overview for IL1A 蛋白 (ABIN935467)
抗原
See all IL1A 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
序列
- SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS
-
产品特性
-
Purified recombinant Mouse IL1 alpha protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of Mouse D10S cells is 5 x 10^8 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
-
缓冲液
- Lyophilized from 5 mM tris, pH 8.0.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- RT/-20 °C
-
-
- IL1A (Interleukin 1 alpha (IL1A))
-
别名
- IL1 alpha
-
背景
-
IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.
Alternative Names: Hematopoietin-1 protein, IL 1 protein, MCF protein, LAF protein, Lymphocyte-activating factor protein, IL 1, Leukocyte Endogenous Mediator protein, IL-1 alpha protein, Mononuclear Cell Factor protein, Endogenous Pyrogen protein, Interleukin 1 alpha protein, LEM protein, EP protein, IL1, IL-1 protein, IL-1 -
分子量
- 17.9 kDa
-
途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
-