Purified recombinant Mouse IL1 alpha protein Expression System: E.coli Bioactivity: The ED50 as determined by the dose-dependent stimulation of Mouse D10S cells is 5 x 10^8 units/mg.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
缓冲液
Lyophilized from 5 mM tris, pH 8.0.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
RT/-20 °C
抗原
IL1A
(Interleukin 1 alpha (IL1A))
别名
IL1 alpha
背景
IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine. Alternative Names: Hematopoietin-1 protein, IL 1 protein, MCF protein, LAF protein, Lymphocyte-activating factor protein, IL 1, Leukocyte Endogenous Mediator protein, IL-1 alpha protein, Mononuclear Cell Factor protein, Endogenous Pyrogen protein, Interleukin 1 alpha protein, LEM protein, EP protein, IL1, IL-1 protein, IL-1