TNFSF13 蛋白
-
- 抗原 See all TNFSF13 蛋白
- TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- Hi-5 Cells
- 序列
- AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL
- 产品特性
-
Purified recombinant Human APRIL protein
Expression System: Hi-5 cells
Bioactivity: Tested by its ability to induce IgM secretion by CpG/CD40L treated human naive B cells, at a concentration of 500ng/mL. - 纯度
- > 95 % pure
- 内毒素水平
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product TNFSF13 蛋白
-
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 说明
-
Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Supplied as a lyophilized powder.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
-
- 抗原
- TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
- 别名
- APRIL (TNFSF13 产品)
- 别名
- APRIL Protein, CD256 Protein, TALL-2 Protein, TALL2 Protein, TRDL-1 Protein, ZTNF2 Protein, 2310026N09Rik Protein, April Protein, Tall2 Protein, Trdl1 Protein, SLAN Protein, ANP32B Protein, april Protein, tnf13 Protein, TNLG7B Protein, TNF superfamily member 13 Protein, tumor necrosis factor (ligand) superfamily, member 13 Protein, acidic leucine-rich nuclear phosphoprotein 32 family member B Protein, TNFSF13 Protein, Tnfsf13 Protein, LOC494442 Protein, tnfsf13 Protein
- 背景
-
APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor.
Alternative Names: TNFSF13 protein, TRDL-1a protein, TRDL-1 alpha protein, A Proliferating-inducing Ligand protein - 分子量
- 16.3 kDa
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
-