The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. Recombinant human MIF was expressed in E. coli and purified by conventional chromatography techniques. Alternative Names: Macrophage migration inhibitory factor protein, Glycosylation-inhibiting factor protein, GIF protein, MIF protein, macrophage migration inhibitory factor (glycosylation-inhibiting factor) protein, EC 5.3.2.1 protein, Macrophage migration inhibitory factor protein, , Phenylpyruvate tautomerase protein, MMIF protein, GLIF protein