SERPINA1
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
蛋白类型
Native
宿主
人
资源
Human
交叉反应 (详细)
When tested with active-site titrated porcine pancreatic trypsin using Na-Benzoyl-L-Arginine-para-Nitroanilide Hydrochloride (L-BAPNA) as substrate, it is 75-100 % inihibitory.
产品特性
Purified native Human alpha 1 Antitrypsin protein Protein Source: Human plasma
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute with distilled water.
缓冲液
Lyophilized from 30 mM Na0 O4, pH 6.5, with 300 M NaCl.
注意事项
Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Aliquot and store at -20 °C.
抗原
SERPINA1
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
AACT Protein, ACT Protein, GIG25 Protein, A1AT Protein, PI Protein, alpha-1-PI Protein, A1A Protein, AAT Protein, PI1 Protein, PRO2275 Protein, alpha1AT Protein, Pi Protein, Spi1 Protein, MGC64429 Protein, serpina1d Protein, Aps Protein, SERPINA3-5 Protein, serpin family A member 3 Protein, alpha-1-antiproteinase F precursor Protein, serpin family A member 1 Protein, alpha-1-antitrypsin Protein, calumenin Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 Protein, SH2B adaptor protein 2 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog Protein, SERPINA3 Protein, LOC100008973 Protein, SERPINA1 Protein, LOC100328621 Protein, CALU Protein, Serpina1 Protein, serpina1.S Protein, serpina1 Protein, SPIA5 Protein, Sh2b2 Protein, Calu Protein, serpina1.L Protein
背景
An acute-phase plasma protein found at 290 mg per 100 ml that functions as a protease inhibitor. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Description: Human plasma. Alternative Names: A1-AT protein, alpha 1 protein, alpha-1 Antitrypsin protein, alpha-1-Antitrypsin, alpha-1-Antitrypsin protein, A1AT protein, alpha 1 Antitrypsin