HIV-1 gp41
宿主: Human Immunodeficiency Virus (HIV)
Recombinant
应用备注
ELISA: 1:500-1:1,000, WB: 1:500-1:1,000
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in sterile distilled water.
缓冲液
Supplied lyophilized from PBS buffer, with no preservatives added,
储存液
Without preservative
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -70 °C for long term storage.
Du, Idiart, Mariano, Chen, Jiang, Xu, Ostrow, Wrin, Phung, Binley, Petropoulos, Ballantyne, Whalen: "Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein." in: Virology, Vol. 395, Issue 1, pp. 33-44, (2009) (PubMed).
Opalka, Pessi, Bianchi, Ciliberto, Schleif, McElhaugh, Danzeisen, Geleziunas, Miller, Eckert, Bramhill, Joyce, Cook, Magilton, Shiver, Emini, Esser: "Analysis of the HIV-1 gp41 specific immune response using a multiplexed antibody detection assay." in: Journal of immunological methods, Vol. 287, Issue 1-2, pp. 49-65, (2004) (PubMed).
抗原
HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)
别名
HIV1 gp41
物质类
Viral Protein
背景
GP41 is a glycoprotein subunit that remains non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4, gp120 changes its conformation, causing gp41 to become exposed, where it can assist in fusion with the host cell. Alternative Names: gp41 antigen, HIV 1 gp41, HIV-1 gp41 protein, gp41 antigen, gp41 glycoprotein antigen, Glycoprotein 41 antigen, Envelope surface glycoprotein gp41 antigen, HIV-1 gp41 antigen, Human Immunodeficiency Virus 1 antigen, HIV1 gp41, Surface protein antigen, SU antigen, HIV 1 gp41 protein, HIV-1 gp41, HIV 1 gp41 antigen