Caspase 9 蛋白
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北京 101111
Quick Overview for Caspase 9 蛋白 (ABIN925032)
抗原
See all Caspase 9 (CASP9) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- 400 units/mg. One unit is the enzyme activity that cleaves 1 nmol of the caspase substrate LEHD-pNA per hour at 37°C in a reaction solution containing 50 mM Hepes, pH 7.2, 50 mM NaCl, 0.1% Chaps, 10 mM EDTA, 5% Glycerol, and 10 mM DTT.
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- -80 °C
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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别名
- Caspase-9
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背景
- Active enzyme was expressed in E. coli. The expressed caspase-9 spontaneously undergoes autoprocessing to yield the subunits characteristic of the native enzyme. One unit of rhCaspase-9 is the enzyme activity that cleaves 1 nmol of substrate Ac-LEHD-pNA per hour at 37°C at standard substrate concentrations. In combination with caspase-9 activity assays, the active rhCaspase-9 is useful in screening caspase inhibitors for pharmaceutical applications. The enzyme is also useful in studying enzyme regulation, determining target substrates and as a positive control in caspase-9 assays.
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途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
抗原
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