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G-CSF 蛋白

CSF3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN871800
发货至: 中国
  • 抗原 See all G-CSF (CSF3) 蛋白
    G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 27
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    资源
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    大肠杆菌(E. Coli)
    序列
    TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
    纯度
    > 98 % by SDS-PAGE and HPLC analyses.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 1EU/µg of rHuG-CSF as determined by LAL method.
    Top Product
    Discover our top product CSF3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C/-20 °C
  • 抗原
    G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
    别名
    G-CSF (CSF3 产品)
    别名
    CSF3 Protein, G-CSF Protein, gcsf Protein, Csfg Protein, MGI-IG Protein, C17orf33 Protein, CSF3OS Protein, GCSF Protein, Gcsf Protein, colony stimulating factor 3 Protein, colony stimulating factor 3 (granulocyte) a Protein, colony stimulating factor 3 (granulocyte) Protein, CSF3 Protein, csf3a Protein, Csf3 Protein
    背景
    G-CSF is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-a and IFN-g. Other cell types including fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells can also secrete G-CSF after LPS, IL-1 or TNF-a activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively. In humans, two distinct cDNA clones for G-CSF, encoding 207 and 204 amino acid precursor proteins, have been isolated. Both proteins have a 30 amino acid signal peptide and have identical amino acid sequences except for a three amino acid insertion (deletion) at the 35th amino acid residue from the N-terminus of the mature protein. Human G-CSF is 73% identical at the amino acid level to murine G-CSF and the two proteins show species cross-reactivity.
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
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