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IL-15 蛋白

IL15 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 96 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN871794
发货至: 中国
  • 抗原 See all IL-15 (IL15) 蛋白
    IL-15 (IL15) (Interleukin 15 (IL15))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 22
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    资源
    • 32
    • 10
    • 10
    • 2
    • 2
    大肠杆菌(E. Coli)
    序列
    MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS
    纯度
    > 96 % by SDS-PAGE and HPLC analyses.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 1EU/µg of rHuIL-15 as determined by LAL method.
    Top Product
    Discover our top product IL15 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C/-20 °C
  • 抗原
    IL-15 (IL15) (Interleukin 15 (IL15))
    别名
    IL-15 (IL15 产品)
    别名
    IL15 Protein, AI503618 Protein, IL-15 Protein, interleukin 15 Protein, IL15 Protein, Il15 Protein
    背景
    Interleukin 15 is a recently identified novel cytokine that shares many biological properties with IL-2, including T, B and NK cell-stimulatory activities. cDNA clones encoding this cytokine have been isolated from simian, murine and human cell sources. Human IL-15 shares approximately 97% and 73% sequence identity with simian and murine IL-15, respectively. Both human and simian IL-15 are active on murine cells. Human IL-15 cDNA encodes a 162 amino acid residue precursor protein containing a 48 amino acid residue signal peptide that is cleaved to yield the 114 amino acid residue mature protein. The IL-15 mRNA is expressed by a wide variety of cells and tissues and is most abundantly expressed by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells. However, in activated peripheral blood T lymphocytes where IL-2 is highly expressed, the expression of IL-15 is not detectable. Although IL-15 lacks sequence homology with IL-2, it has recently been shown that both the beta and gamma chains of the IL-2 receptor are utilized for IL-15 binding and signaling. In addition, an IL-15 specific binding protein has also been cloned from a mouse T cell clone. (Grabstein, K. et al., 1994, Science 264:965, Giri, J. et al., 1994, EMBO J. 13:2822).
    途径
    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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