EPH Receptor B4 Protein (EPHB4) (AA 561-987)
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Quick Overview for EPH Receptor B4 Protein (EPHB4) (AA 561-987) (ABIN7938807)
抗原
See all EPH Receptor B4 (EPHB4) 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 561-987
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原理
- Recombinant EPHB4 (561-987) protein
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EPH Receptor B4 (EPHB4) (AA 1-987) protein (GST tag)
EPHB4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor B4 (EPHB4) (Active) protein (His tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
EPH Receptor B4 (EPHB4) (AA 563-987) (Active) protein (GST tag,His tag)EPHB4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
EPH Receptor B4 (EPHB4) (Active) protein (Fc Tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
EPH Receptor B4 (EPHB4) (AA 16-539) protein (His tag)EPHB4 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant EPHB4 (561-987) protein is supplied in 25 mM HEPESNaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100 and 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- EPH Receptor B4 (EPHB4)
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别名
- EPHB4
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背景
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Protein Background: EPHB4(Ephrin type-B receptor 4) is a Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/ functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.
Short Description: Recombinant EPHB4 (561-987) protein that includes amino acids 561-987 of human EPHB4 protein (accession number NP_004435.3) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 48.89 kDa.
Aliases: Ephrin type-B receptor 4, TYRO11, HTK, MYK1, Tyrosine-Protein Kinase Receptor HTK
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途径
- RTK signaling
抗原
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