EPH Receptor B4 Protein (EPHB4) (AA 563-987) (His-GST)
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北京 101111
Quick Overview for EPH Receptor B4 Protein (EPHB4) (AA 563-987) (His-GST) (ABIN7317112)
抗原
See all EPH Receptor B4 (EPHB4) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 563-987
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标记
- This EPH Receptor B4 protein is labelled with His-GST.
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原理
- Recombinant Human EphB4/HTK Protein (aa 563-987, His & GST Tag)
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序列
- Leu563-Tyr987
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产品特性
- A DNA sequence encoding the human EPHB4 (P54760) (Leu563-Tyr987) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be 47 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
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EPH Receptor B4 (EPHB4) (AA 1-987) protein (GST tag)
EPHB4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
EPH Receptor B4 (EPHB4) (AA 16-539) protein (His tag)EPHB4 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % SDS
EPH Receptor B4 (EPHB4) (Active) protein (His tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by reducing SDS-PAGE. ELISA Active
EPH Receptor B4 (EPHB4) (Active) protein (Fc Tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. ELISA Active
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 8.0, 3 mM DTT, 10 % glycerol
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- EPH Receptor B4 (EPHB4)
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别名
- EphB4/HTK
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背景
- HTK,MYK1,TYRO11,Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
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分子量
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Calculated MW: 75.2 kDa
Observed MW: 66 kDa
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基因ID
- 2050
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UniProt
- P54760
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途径
- RTK signaling
抗原
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