IL1A 蛋白
Our Local Distributor
北京 101111
Quick Overview for IL1A 蛋白 (ABIN7849710)
抗原
See all IL1A 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
原理
- Recombinant Mouse IL-1a Protein
-
过滤
- 0.2 μm filtered
-
内毒素水平
- <1 EU/μg by LAL test
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 6 % Sucrose, 2 %Mannitol, 50 mM Arginine, 0.03 % Tween80, pH 8.0.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
-
-
- IL1A (Interleukin 1 alpha (IL1A))
-
别名
- IL-1a
-
背景
-
Synonyms: IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha, IL-1 alpha, IL-1α
Description: Recombinant mouse IL-1a is produced by the E.coli system, with the target gene encoding Ser115-Ser270 expressed.
Background: Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.
-
UniProt
- P01583
-
途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
-