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IL1A 蛋白

This Recombinant IL1A protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7849706
发货至: 中国
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Quick Overview for IL1A 蛋白 (ABIN7849706)

抗原

See all IL1A 蛋白
IL1A (Interleukin 1 alpha (IL1A))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

>95 % by SDS-PAGE
  • 原理

    Recombinant Human IL-1a Protein

    过滤

    0.2 μm filtered

    内毒素水平

    <0.01 EU/μg by LAL test
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
  • 抗原

    IL1A (Interleukin 1 alpha (IL1A))

    别名

    IL-1a

    背景

    Synonyms: IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha, IL-1 alpha, IL-1α

    Description: Recombinant human IL-1a is produced by the E.coli system, with the target gene encoding Ser113-Ala271 expressed.

    Background: Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.

    UniProt

    P01583

    途径

    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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