GDNF 蛋白
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北京 101111
Quick Overview for GDNF 蛋白 (ABIN7849696)
抗原
See all GDNF 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human GDNF Protein
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过滤
- 0.2 μm filtered
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内毒素水平
- <1 EU/μg by LAL test
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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别名
- GDNF
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背景
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Synonyms: GDNF, ATF1, ATF2, glial cell derived neurotrophic factor, HFB1-HSCR3, ATF
Description: Recombinant human GDNF is produced by the E.coli system, with the target gene encoding Ser78-Ile211 expressed.
Background: Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene.GDNF is a small protein that potently promotes the survival of many types of neurons.It signals through GFRα receptors, particularly GFRα1. It is also responsible for the determination of spermatogonia into primary spermatocytes, i.e. it is received by RET proto-oncogene (RET) and by forming gradient with SCF it divides the spermatogonia into two cells. As the result there is retention of spermatogonia and formation of spermatocyte.
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UniProt
- P39905
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途径
- RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
抗原
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