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IL1A 蛋白

This Recombinant IL1A protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7849667
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for IL1A 蛋白 (ABIN7849667)

抗原

See all IL1A 蛋白
IL1A (Interleukin 1 alpha (IL1A))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS), ELISA

纯度

>90 % by SDS-PAGE
  • 原理

    Recombinant Human Interleukin-1 alpha, IL1A Protein
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM Tris-HCl, pH 7.4±0.2.

    储存条件

    4 °C,-20 °C

    储存方法

    Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.
  • 抗原

    IL1A (Interleukin 1 alpha (IL1A))

    别名

    IL1A

    背景

    Synonyms: Interleukin-1 alpha, IL1A, IL-1 alpha, Hematopoietin-1, IL1F1, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha.

    Description: Recombinant human IL-1 alpha protein.

    Background: Interleukin-1 alpha (IL-1α) is a protein of the interleukin-1 family that in humans is encoded by the IL1A gene which spans 10.2 kb and has 7 exons. It is 1 of 2 structurally distinct forms of IL1, the other being IL1B, this two proteins are synthesized by a variety of cell types, including activated macrophages, keratinocytes, stimulated B lymphocytes, and fibroblasts, and are potent mediators of inflammation and immunity. IL1A may play a role in the genesis of inflammation by augmenting the transcription of proinflammatory genes, a mechanism not affected by extracellular inhibitors. IL1A has been administered to patients during receiving autologous bone marrow transplantation.

    途径

    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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