IL1A 蛋白
Our Local Distributor
北京 101111
Quick Overview for IL1A 蛋白 (ABIN7849667)
抗原
See all IL1A 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
原理
- Recombinant Human Interleukin-1 alpha, IL1A Protein
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 10 mM Tris-HCl, pH 7.4±0.2.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.
-
-
- IL1A (Interleukin 1 alpha (IL1A))
-
别名
- IL1A
-
背景
-
Synonyms: Interleukin-1 alpha, IL1A, IL-1 alpha, Hematopoietin-1, IL1F1, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha.
Description: Recombinant human IL-1 alpha protein.
Background: Interleukin-1 alpha (IL-1α) is a protein of the interleukin-1 family that in humans is encoded by the IL1A gene which spans 10.2 kb and has 7 exons. It is 1 of 2 structurally distinct forms of IL1, the other being IL1B, this two proteins are synthesized by a variety of cell types, including activated macrophages, keratinocytes, stimulated B lymphocytes, and fibroblasts, and are potent mediators of inflammation and immunity. IL1A may play a role in the genesis of inflammation by augmenting the transcription of proinflammatory genes, a mechanism not affected by extracellular inhibitors. IL1A has been administered to patients during receiving autologous bone marrow transplantation.
-
途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
-