Sclerostin Protein (SOST) (AA 24-213) (His tag)
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Quick Overview for Sclerostin Protein (SOST) (AA 24-213) (His tag) (ABIN7669713)
抗原
See all Sclerostin (SOST) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 24-213
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标记
- This Sclerostin protein is labelled with His tag.
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原理
- Recombinant Human SOST Protein (His Tag)
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序列
- Gln24-Tyr213
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method
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Biological Activity Comment
- Not validated for activity
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Sclerostin (SOST) (AA 24-213) protein (His-Avi Tag)
SOST 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sclerostin (SOST) (AA 24-213) (Active) protein (Biotin,His-Avi Tag)SOST 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Sclerostin (SOST) (AA 69-258) (Active) protein (His tag)SOST 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Sclerostin (SOST) (AA 24-211) protein (His tag)SOST 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Sclerostin (SOST) protein (His tag)SOST 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE.
Sclerostin (SOST) (AA 24-213) protein (His tag,Biotin)SOST 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Sclerostin (SOST)
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别名
- SOST
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背景
- CDD,DAND6,SOST1,VBCH,Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
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分子量
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Calculated MW: 20.8 kDa
Observed MW: 28 kDa
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基因ID
- 50964
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UniProt
- Q9BQB4
抗原
-
