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Sclerostin Protein (SOST) (His tag)

This Recombinant Sclerostin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7669713
发货至: 中国
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Quick Overview for Sclerostin Protein (SOST) (His tag) (ABIN7669713)

抗原

See all Sclerostin (SOST) 蛋白
Sclerostin (SOST)

蛋白类型

Recombinant

生物活性

Inactive

宿主

  • 7
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资源

  • 6
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大肠杆菌(E. Coli)

纯度

> 95 %
  • 标记

    This Sclerostin protein is labelled with His tag.

    原理

    Recombinant Human SOST protein (His tag)

    序列

    Gln 24-Tyr 213

    过滤

    0.2 μm filtered

    内毒素水平

    < 10 EU/mg of the protein as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Sclerostin (SOST)

    别名

    SOST

    背景

    Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.,CDD,DAND6,SOST1,VBCH

    分子量

    calculated_mw: 20.8 kDa

    observed_mw: 28 kDa

    UniProt

    Q9BQB4
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