SFRP2 Protein (AA 25-295) (His tag)
-
- 抗原 See all SFRP2 蛋白
- SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-295
-
宿主
- 小鼠
-
资源
- Baculovirus infected Insect Cells
- 标记
- This SFRP2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
-
LFLFGQP DFSYKRSNCK PIPANLQLCH GIEYQNMRLP NLLGHETMKE VLEQAGAWIP LVMKQCHPDT KKFLCSLFAP VCLDDLDETI QPCHSLCVQV KDRCAPVMSA FGFPWPDMLE CDRFPQDNDL CIPLASSDHL LPATEEAPKV CEACKTKNED DNDIMETLCK NDFALKIKVK EITYINRDTK IILETKSKTI YKLNGVSERD LKKSVLWLKD SLQCTCEEMN DINAPYLVMG QKQGGELVIT SVKRWQKGQR EFKRISRSIR KLQC - 纯度
- > 90% by SDS-PAGE
- 内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product SFRP2 蛋白
-
Secreted Frizzled-Related Protein 2 (SFRP2) (AA 25-295) protein (His tag)
SFRP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Secreted Frizzled-Related Protein 2 (SFRP2) (AA 25-295) protein (His tag)SFRP2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Secreted Frizzled-Related Protein 2 (SFRP2) (AA 25-171) protein (His-IF2DI Tag)SFRP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
- 抗原
- SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))
- 别名
- sFRP-2/SFRP2 (SFRP2 产品)
- 背景
- SFRP-2, also known as Secreted apoptosis-related protein 1, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. sFRP-2 can exert either positive or negative effects on Wnt signaling. At physiological concentrations, it also inhibits BMP-induced effects. It plays a variety of roles during tissue morphogenesis including inhibition of the planar cell polarity pathway and myoblast and osteoblast differentiation. It is also expressed in multiple myeloma and glioma in which it promotes tumorigenicity. Recombinant mouse sFRP-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 32.1kDa (280aa)
- NCBI登录号
- NP_033170
- 途径
- WNT signaling, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation
-
