FASL Protein (AA 1-279) (His tag)
Quick Overview for FASL Protein (AA 1-279) (His tag) (ABIN7563219)
抗原
See all FASL 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-279
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标记
- This FASL protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Faslg Protein expressed in mammalian cells.
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序列
- MQQPMNYPCP QIFWVDSSAT SSWAPPGSVF PCPSCGPRGP DQRRPPPPPP PVSPLPPPSQ PLPLPPLTPL KKKDHNTNLW LPVVFFMVLV ALVGMGLGMY QLFHLQKELA ELREFTNQSL KVSSFEKQIA NPSTPSEKKE PRSVAHLTGN PHSRSIPLEW EDTYGTALIS GVKYKKGGLV INETGLYFVY SKVYFRGQSC NNQPLNHKVY MRNSKYPEDL VLMEEKRLNY CTTGQIWAHS SYLGAVFNLT SADHLYVNIS QLSLINFEES KTFFGLYKL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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想要此Protein的其他选项吗？
!探索我们的目录蛋白和定制蛋白服务选项！Product表达系统ConjugateOriginPrice表达系统 Mammalian CellsConjugate His tagOrigin MousePrice 4,971.42 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin MousePrice 4,995.01 ¥表达系统 Escherichia coli (E. coli)Conjugate His tag,GST tagOrigin MousePrice 5,533.39 ¥表达系统 HEK-293 CellsConjugate DYKDDDDK TagOrigin Human, MousePrice 6,557.74 ¥表达系统 HEK-293 CellsConjugate DYKDDDDK TagOrigin Human, MousePrice 11,178.06 ¥表达系统 HEK-293 CellsConjugate Fc TagOrigin Human, MousePrice 18,630.02 ¥表达系统 HEK-293T CellsConjugate DYKDDDDK TagOrigin Human, Mouse, RatPrice 9,336.40 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-281) protein (His tag)
custom-made FASL 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 134-281) (Active) protein (His tag)FASL 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fas Ligand (TNF Superfamily, Member 6) (FASL) protein (Fc Tag)FASL 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-281) protein (GST tag)FASL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fas Ligand (TNF Superfamily, Member 6) (FASL) proteinFASL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- Faslg
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背景
- Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL), ADAM10-processed FasL form (APL), FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)],FUNCTION: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:7511063). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494, PubMed:7532682). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed:19794494). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed:10779162). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity). {ECO:0000250|UniProtKB:P48023, ECO:0000269|PubMed:19794494, ECO:0000269|PubMed:7511063, ECO:0000269|PubMed:7532682}., FUNCTION: [Tumor necrosis factor ligand superfamily member 6, soluble form]: Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways (PubMed:19794494). Can induce apoptosis but does not appear to be essential for this process (By similarity). {ECO:0000250|UniProtKB:P48023, ECO:0000269|PubMed:19794494}., FUNCTION: [FasL intracellular domain]: Cytoplasmic form induces gene transcription inhibition. {ECO:0000250|UniProtKB:P48023}.
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分子量
- 31.4 kDa
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UniProt
- P41047
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AlphaFold
- P41047
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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