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FZD1 蛋白

This Synthetic Nanodisc FZD1 protein is expressed in Mammalian Cells.
产品编号 ABIN7538243
发货至: 中国

Quick Overview for FZD1 蛋白 (ABIN7538243)

抗原

See all FZD1 (Fzd1) 蛋白
FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

蛋白类型

Synthetic Nanodisc

宿主

  • 5
  • 4

资源

  • 3
  • 3
  • 2
Mammalian Cells
  • 原理

    Human FZD1 full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

    别名

    FZD1

    背景

    Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008]

    分子量

    The human full length FZD1 protein has a MW of 71.2kDa

    UniProt

    Q9UP38

    途径

    WNT signaling, Asymmetric Protein Localization
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