SIRPB1 Protein (His tag)
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- 抗原 See all SIRPB1 蛋白
- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SIRPB1 protein is labelled with His tag.
- 原理
- Recombinant Human SIRP-beta-1/SIRPB1/CD172b Protein
- 序列
- EDELQVIQPE KSVSVAAGES ATLRCAMTSL IPVGPIMWFR GAGAGRELIY NQKEGHFPRV TTVSELTKRN NLDFSISISN ITPADAGTYY CVKFRKGSPD DVEFKSGAGT ELSVRAKPSA PVVSGPAVRA TPEHTVSFTC ESHGFSPRDI TLKWFKNGNE LSDFQTNVDP AGDSVSYSIH STARVVLTRG DVHSQVICEI AHITLQGDPL RGTANLSEAI RVPPTLEVTQ QPMRAENQAN VTCQVSNFYP RGLQLTWLEN GNVSRTETAS TLIENKDGTY NWMSWLLVNT CAHRDDVVLT CQVEHDGQQA VSKSYALEIS AHQKEHGSDI THEAALAPTA PL
- 特异性
- Glu30-Leu371
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <0.1EU/μg
- Top Product
- Discover our top product SIRPB1 蛋白
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Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-371), (Isoform 3) protein (His-Avi Tag)
SIRPB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-371), (Isoform 3) protein (His-Avi Tag,Biotin)SIRPB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Signal-Regulatory Protein beta 1 (SIRPB1) (AA 1-181) protein (GST tag)SIRPB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-371) protein (His tag)Crystallography grade SIRPB1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-398) protein (rho-1D4 tag)Crystallography grade SIRPB1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Signal-Regulatory Protein beta 1 (SIRPB1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SIRPB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
- 别名
- SIRP-beta-1/SIRPB1/CD172b (SIRPB1 产品)
- 别名
- CD172b Protein, SIRP-BETA-1 Protein, SIRPB1 Protein, SIRPG Protein, signal regulatory protein beta 1 Protein, signal-regulatory protein beta-1 Protein, signal-regulatory protein beta-1 isoform 3 Protein, SIRPB1 Protein, LOC458036 Protein, LOC458430 Protein, LOC485809 Protein, LOC715912 Protein, LOC100458151 Protein
- 背景
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Description: Signal-regulatory protein beta-1 (SIRP beta 1) also known as SIRP1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily.Signal-regulatory proteins (SIRPs) are cell-surface glycoproteins expressed on myeloid and neural cells that have been shown to recruit SH2 domain-containing protein phosphatase 1 (SHP-1) and SHP-2 and to regulate receptor tyrosine kinase-coupled signaling. SIRP are classified as SIRP alpha molecules, containing 11- to 113-amino acid long, or SIRP beta molecules, with a 5-amino acid long intracytoplasmic domain. SIRP beta 1 is a new DAP12-associated receptor involved in the activation of myeloid cells, which contains a short cytoplasmic domain that lacks sequence motifs capable of recruiting SHP-1 and SHP-2. SIRP beta 1 acts as an activating isoform of SIRP alpha molecules, confirming the co-existence of inhibitory ITIM-bearing molecules, recruiting SHP-1 and SHP-2 protein tyrosine phosphatases, and activating counterparts, whose engagement couples to protein tyrosine kinases via ITAM-bearing molecules.
Name: 9930027N05Rik,SIRP-beta,Sirpb,Sirpb1,SIRPB1
- 基因ID
- 10326
- UniProt
- O00241
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