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REG4 Protein (His tag)

REG4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7535389
发货至: 中国
  • 抗原 See all REG4 蛋白
    REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 5
    • 3
    资源
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This REG4 protein is labelled with His tag.
    原理
    Recombinant Human REG-4 Protein
    序列
    MASRSMRLLL LLSCLAKTGV LGDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP
    特异性
    Met1-Pro158
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Top Product
    Discover our top product REG4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
    别名
    REG-4 (REG4 产品)
    别名
    GISP Protein, REG-IV Protein, RELP Protein, 2010002L15Rik Protein, regenerating family member 4 Protein, regenerating islet-derived family, member 4 Protein, Reg4 Protein, REG4 Protein
    背景

    Description: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.

    Name: REG4,GISP,REG-IV,RELP

    基因ID
    83998
    UniProt
    Q9BYZ8-1
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