MITF Protein (rFc Tag)
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- 抗原 See all MITF 蛋白
- MITF (Microphthalmia-Associated Transcription Factor (MITF))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MITF protein is labelled with rFc Tag.
- 原理
- Recombinant Human MITF Protein
- 序列
- HGLSLIPSTG LCSPDLVNRI IKQEPVLENC SQDLLQHHAD LTCTTTLDLT DGTITFNNNL GTGTEANQAY SVPTKMGSKL EDILMDDTLS PVGVTDPLLS SVSPGASKTS SRRSSMSMEE TEHTC
- 特异性
- His402-Cys526
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <0.1EU/μg
- Top Product
- Discover our top product MITF 蛋白
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Microphthalmia-Associated Transcription Factor (MITF) (AA 1-223) protein (His-IF2DI Tag)
MITF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Microphthalmia-Associated Transcription Factor (MITF) (AA 1-520) protein (GST tag)MITF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Microphthalmia-Associated Transcription Factor (MITF) (AA 1-526) protein (Strep Tag)Crystallography grade MITF 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Microphthalmia-Associated Transcription Factor (MITF) (AA 1-526) protein (Strep Tag)Crystallography grade MITF 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- MITF (Microphthalmia-Associated Transcription Factor (MITF))
- 别名
- MITF (MITF 产品)
- 别名
- MITF Protein, ws2a Protein, mitfa Protein, MITF-A Protein, LOC100313655 Protein, mitfb Protein, CMM8 Protein, MI Protein, WS2 Protein, WS2A Protein, bHLHe32 Protein, BCC2 Protein, Bhlhe32 Protein, Gsfbcc2 Protein, Vitiligo Protein, Wh Protein, bw Protein, mi Protein, vit Protein, MITF-H Protein, MITF-M Protein, CMI9 Protein, melanogenesis associated transcription factor Protein, microphthalmia-associated transcription factor Protein, microphthalmia-associated transcription factor S homeolog Protein, Microphthalmia Protein, MITF Protein, mitf Protein, LOC100313655 Protein, mitf.S Protein, LOC100534525 Protein, MICROP Protein, Mitf Protein
- 背景
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Description: Microphthalmia-associated transcription factor (MITF) is a member of the basic helix-loop-helix leucine zipper (bHLH-Zip) family and functions as the master regulator of the melanocytic lineage.MITF (Microphthalmia-associated transcription factor) is a lineage-specific transcription factor that plays a critical role in melanocyte homeostasis and whose deregulation has been shown to contribute to melanoma disease. Microphthalmia-associated transcription factor (MITF) is expressed in melanomas and has a critical role in melanocyte development and transformation. Because inhibition of MITF inhibits cell growth in melanoma, MITF is a potential therapeutic target molecule. Microphthalmia-associated transcription factor (MITF) regulates the transcription of its target genes by binding to their promoters. Microphthalmia-associated transcription factor (MITF) is a key regulator of differentiation of melanocytes and retinal pigment epithelial cells, but it also has functions in non-pigment cells.
Name: CMM8, COMMAD, MI, WS2, WS2A, bHLHe32,MITF,COMMAD,MI,WS2,WS2A,bHLHe32
- 基因ID
- 4286
- UniProt
- O75030
- 途径
- Chromatin Binding
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