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Lipocalin 2 Protein (LCN2)

LCN2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 97 % by SDS-PAGE. Active
产品编号 ABIN7533745
发货至: 中国
  • 抗原 See all Lipocalin 2 (LCN2) 蛋白
    Lipocalin 2 (LCN2)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 11
    • 7
    • 6
    • 2
    • 1
    • 1
    资源
    • 10
    • 10
    • 2
    • 2
    • 1
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    Baculovirus infected Insect Cells
    原理
    Recombinant Human Lipocalin-2/NGAL/LCN2 Protein
    序列
    QDSTSDLIPA PPLSKVPLQQ NFQDNQFQGK WYVVGLAGNA ILREDKDPQK MYATIYELKE DKSYNVTSVL FRKKKCDYWI RTFVPGCQPG EFTLGNIKSY PGLTSYLVRV VSTNYNQHAM VFFKKVSQNR EYFKITLYGR TKELTSELKE NFIRFSKSLG LPENHIVFPV PIDQCIDG
    特异性
    Gln21-Gly198
    纯度
    > 97 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 1.0 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its ability to bind Iron(III) dihydroxybenzoic acid [Fe(DHBA)3]. The binding of Fe(DHBA)3 results in the quenching of Trp fluorescence in recombinant human Lipocalin-2. Recombinant human Lipocalin-2 can bind >10625 μM of Fe(DHBA)3.
    Top Product
    Discover our top product LCN2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    Lipocalin 2 (LCN2)
    别名
    Lipocalin-2/NGAL/LCN2 (LCN2 产品)
    别名
    LCN2 Protein, 24p3 Protein, MSFI Protein, NGAL Protein, AW212229 Protein, Sip24 Protein, lipocalin 2 Protein, LCN2 Protein, Lcn2 Protein
    背景

    Description: Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.

    Name: 24p3, MSFI, NGAL, p25,LCN2,MSFI,NGAL,p25

    基因ID
    3934
    UniProt
    P80188
    途径
    Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
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