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Lipocalin 1 Protein (LCN1) (His tag)

LCN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
产品编号 ABIN7520291
发货至: 中国
  • 抗原 See all Lipocalin 1 (LCN1) 蛋白
    Lipocalin 1 (LCN1)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 6
    • 3
    • 2
    • 1
    • 1
    资源
    • 7
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This Lipocalin 1 protein is labelled with His tag.
    原理
    Active Recombinant Human Lipocalin-1/LCN1 Protein
    序列
    HHLLASDEEI QDVSGTWYLK AMTVDREFPE MNLESVTPMT LTTLEGGNLE AKVTMLISGR CQEVKAVLEK TDEPGKYTAD GGKHVAYIIR SHVKDHYIFY CEGELHGKPV RGVKLVGRDP KNNLEALEDF EKAAGARGLS TESILIPRQS ETCSPGSD
    特异性
    His19-Asp176
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Biological Activity Comment
    Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value is <2.94 nM.
    Top Product
    Discover our top product LCN1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    Lipocalin 1 (LCN1)
    别名
    Lipocalin-1/LCN1 (LCN1 产品)
    别名
    PMFA Protein, TLC Protein, TP Protein, VEGP Protein, VEG Protein, lipocalin 1 Protein, odorant binding protein 2B Protein, lipocalin-1 Protein, LCN1 Protein, OBP2B Protein, Lcn1 Protein, LOC103346758 Protein
    背景

    Description: Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been found in the rat, pig, and probably dog and horse. Lipocalin-1 / VEGP is an unusual lipocalin member, because of its high promiscuity for relative insoluble lipids and binding characteristics that differ from other members. Lipocalin-1 / VEGP acts as the principal lipid-binding protein in tear fluid, a more general physiological function has to be proposed due to its wide distribution and properties. Lipocalin-1 / VEGP would be ideally suited for scavenging of lipophilic, potentially harmful substances and thus might act as a general protection factor of epithelia. Lipocalin-1 / LCN1 could play a role in taste reception. It could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Lipocalin-1 / LCN1 can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. It exhibits an extremely wide ligand pocket.

    Name: LCN1,PMFA,TLC,TP,VEGP

    基因ID
    3933
    UniProt
    P31025
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