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LAIR2 Protein (His tag)

LAIR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % by SDS-PAGE. Active
产品编号 ABIN7520289
发货至: 中国
  • 抗原 See all LAIR2 蛋白
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    资源
    • 8
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This LAIR2 protein is labelled with His tag.
    原理
    Active Recombinant Human LAIR-2/CD306 Protein
    序列
    QEGALPRPSI SAEPGTVISP GSHVTFMCRG PVGVQTFRLE REDRAKYKDS YNVFRLGPSE SEARFHIDSV SEGNAGLYRC LYYKPPGWSE HSDFLELLVK ESSGGPDSPD TEPGSSAGTV PGTEASGFDA P
    特异性
    Gln22-Pro152
    纯度
    > 90 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 5 x 104 cells/well are added to rhLAIR-2 coated plates (50 μg/mL with 100 μL/well), approximately 50%-60% will adhere after 10 minutes at 37°C.
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    Discover our top product LAIR2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    别名
    LAIR-2/CD306 (LAIR2 产品)
    别名
    CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
    背景

    Description: Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD36, is a 131 amino acid protein containing one lg-like C2-type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83 % aa identity across the signal sequence and extracellular domains, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. LAIR2 is thought to be secreted and may help modulate mucosal tolerance.

    Name: LAIR2,CD306

    基因ID
    3904
    UniProt
    Q6ISS4
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