KIR2DL1 Protein (His tag,AVI tag)
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- 抗原 See all KIR2DL1 蛋白
- KIR2DL1 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This KIR2DL1 protein is labelled with His tag,AVI tag.
- 原理
- Active Recombinant Human NKAT-1/KIR2DL1/CD158a Protein
- 序列
- HEGVHRKPSL LAHPGPLVKS EETVILQCWS DVMFEHFLLH REGMFNDTLR LIGEHHDGVS KANFSISRMT QDLAGTYRCY GSVTHSPYQV SAPSDPLDIV IIGLYEKPSL SAQPGPTVLA GENVTLSCSS RSSYDMYHLS REGEAHERRL PAGPKVNGTF QADFPLGPAT HGGTYRCFGS FHDSPYEWSK SSDPLLVSVT GNPSNSWPSP TEPSSKTGNP R
- 特异性
- His22-Arg242
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized Human KIR2DL1 at 1μg/mL (100 μL/well) can bind KIR2DL1 Rabbit pAb with a linear range of 1-99 ng/mL.
- Top Product
- Discover our top product KIR2DL1 蛋白
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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) protein (His-Avi Tag)
KIR2DL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) protein (His-Avi Tag,Biotin)KIR2DL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 1-374) protein (GST tag)KIR2DL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 22-245) protein (His tag)Crystallography grade KIR2DL1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 22-348) protein (rho-1D4 tag)Crystallography grade KIR2DL1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- KIR2DL1 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
- 别名
- NKAT-1/KIR2DL1/CD158a (KIR2DL1 产品)
- 别名
- NKAT Protein, NKAT1 Protein, p58.1 Protein, CD158A Protein, KIR221 Protein, KIR-K64 Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 Protein, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 Protein, KIR2DL1 Protein
- 背景
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Description: Killer cell immunoglobulin-like receptor 2DL1 or KIR2DL1 is an inhibitory Natural Killer cell immunoglobulin-like receptor with two extracellular immunoglobulin domains. KIR2DL1 is a member of the Killer cell immunoglobulin-like receptor family whose members are classified by the number of the extracellular immunoglobulin domains and the length of the cytoplasm domain. KIR2DL1 is a transmembrane glycoprotein expressed by natural killer cells and subsets of T cells. KIR2DL1 down-regulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. It has been reported that the KIR2DL1 is bound to its class I MHC ligand, HLA-Cw4. The KIR2DL1-HLA-Cw4 interface exhibits charge and shape complementarity. Specificity is mediated by a pocket in KIR2DL1 that hosts the Lys80 residue of HLA-Cw4. Many residues conserved in HLA-C and KIR2DL receptors make different interactions in KIR2DL1-HLA-Cw4 and a previously reported KIR2DL2-HLA-Cw3 complex. A dimeric aggregate of KIR-HLA-C complexes was observed in one KIR2DL1-HLA-Cw4 crystal.
Name: KIR2DL1,CD158A,KIR-K64,KIR221,NKAT,NKAT-1,NKAT1,p58.1
- 基因ID
- 3802
- UniProt
- P43626
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