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CHI3L1 Protein (His tag)

CHI3L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7535291
发货至: 中国
  • 抗原 See all CHI3L1 蛋白
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 5
    • 4
    • 1
    • 1
    HEK-293 Cells
    标记
    This CHI3L1 protein is labelled with His tag.
    原理
    Recombinant Human YKL-40/CHI3L1 Protein
    序列
    YKLVCYYTSW SQYREGDGSC FPDALDRFLC THIIYSFANI SNDHIDTWEW NDVTLYGMLN TLKNRNPNLK TLLSVGGWNF GSQRFSKIAS NTQSRRTFIK SVPPFLRTHG FDGLDLAWLY PGRRDKQHFT TLIKEMKAEF IKEAQPGKKQ LLLSAALSAG KVTIDSSYDI AKISQHLDFI SIMTYDFHGA WRGTTGHHSP LFRGQEDASP DRFSNTDYAV GYMLRLGAPA SKLVMGIPTF GRSFTLASSE TGVGAPISGP GIPGRFTKEA GTLAYYEICD FLRGATVHRI LGQQVPYATK GNQWVGYDDQ ESVKSKVQYL KDRQLAGAMV WALDLDDFQG SFCGQDLRFP LTNAIKDALA AT
    特异性
    Tyr22-Thr383
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Top Product
    Discover our top product CHI3L1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    别名
    YKL-40/CHI3L1 (CHI3L1 产品)
    别名
    AW208766 Protein, Brp39 Protein, Gp39 Protein, ASRT7 Protein, CGP-39 Protein, GP-39 Protein, GP39 Protein, HC-gp39 Protein, HCGP-3P Protein, YKL-40 Protein, YKL40 Protein, YYL-40 Protein, hCGP-39 Protein, GP38K Protein, CLP-1 Protein, SPC-40 Protein, SPS-40 Protein, Chil1 Protein, BP40 Protein, MGP-40 Protein, chitinase-like 1 Protein, chitinase 3 like 1 Protein, chitinase 3-like 1 (cartilage glycoprotein-39) Protein, Chil1 Protein, CHI3L1 Protein, Chi3l1 Protein
    背景

    Description: Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.

    Name: CHI3L1,ASRT7,CGP-39,GP-39,GP39,HC-gp39,HCGP-3P,YKL-40,YKL40,YYL-40,hCGP-39

    基因ID
    1116
    UniProt
    P36222
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