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CD69 Protein (CD69) (His tag)

CD69 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7533873
发货至: 中国
  • 抗原 See all CD69 蛋白
    CD69
    蛋白类型
    Recombinant
    宿主
    • 11
    • 5
    • 3
    • 1
    资源
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD69 protein is labelled with His tag.
    原理
    Recombinant Human CD69 Protein
    序列
    SVGQYNCPGQ YTFSMPSDSH VSSCSEDWVG YQRKCYFIST VKRSWTSAQN ACSEHGATLA VIDSEKDMNF LKRYAGREEH WVGLKKEPGH PWKWSNGKEF NNWFNVTGSD KCVFLKNTEV SSMECEKNLY WICNKPYK
    特异性
    Ser62-Lys199
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product CD69 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    CD69
    别名
    CD69 (CD69 产品)
    别名
    5830438K24Rik Protein, AI452015 Protein, AIM Protein, VEA Protein, BL-AC/P26 Protein, CLEC2C Protein, EA1 Protein, GP32/28 Protein, MLR-3 Protein, Cd69 molecule Protein, CD69 antigen Protein, CD69 molecule Protein, Cd69 Protein, CD69 Protein
    背景

    Description: Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients.

    Name: CD69,AIM,BL-AC/P26,CLEC2C,EA1,GP32/28,MLR-3

    基因ID
    969
    UniProt
    Q07108
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