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APOH Protein (His tag)

APOH 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7535692
发货至: 中国
  • 抗原 See all APOH 蛋白
    APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
    蛋白类型
    Recombinant
    宿主
    • 9
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    资源
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    HEK-293 Cells
    标记
    This APOH protein is labelled with His tag.
    原理
    Recombinant Human Apolipoprotein H/ApoH Protein
    序列
    GRTCPKPDDL PFSTVVPLKT FYEPGEEITY SCKPGYVSRG GMRKFICPLT GLWPINTLKC TPRVCPFAGI LENGAVRYTT FEYPNTISFS CNTGFYLNGA DSAKCTEEGK WSPELPVCAP IICPPPSIPT FATLRVYKPS AGNNSLYRDT AVFECLPQHA MFGNDTITCT THGNWTKLPE CREVKCPFPS RPDNGFVNYP AKPTLYYKDK ATFGCHDGYS LDGPEEIECT KLGNWSAMPS CKASCKVPVK KATVVYQGER VKIQEKFKNG MLHGDKVSFF CKNKEKKCSY TEDAQCIDGT IEVPKCFKEH SSLAFWKTDA SDVKPC
    特异性
    Gly20-Cys345
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Top Product
    Discover our top product APOH 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
    别名
    Apolipoprotein H/ApoH (APOH 产品)
    别名
    B2G1 Protein, B2GP1 Protein, BG Protein, BETA2 Protein, BHF-1 Protein, MODY6 Protein, NEUROD Protein, bHLHa3 Protein, apoh Protein, APOH Protein, B2GPI Protein, beta-2-GPI Protein, beta2-GPI Protein, LOC100227913 Protein, apolipoprotein H Protein, neuronal differentiation 1 Protein, APOH Protein, NEUROD1 Protein, apoh Protein, Apoh Protein
    背景

    Description: Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. It is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. APOH binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. APOH may prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. APOH appears to completely inhibit serotonin release by the platelets and prevents subsequent waves of the ADP-induced aggregation. The activity of APOH appears to involve the binding of agglutenating, negatively charged compounds, and inhibits agglutenation by the contact activation of the intrinsic blood coagulation pathway.

    Name: APOH,B2G1,B2GP1,BG

    基因ID
    350
    UniProt
    P02749
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