APLP1 Protein (His tag)
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- 抗原 See all APLP1 蛋白
- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This APLP1 protein is labelled with His tag.
- 原理
- Recombinant Human APLP-1 Protein
- 序列
- SLAGGSPGAA EAPGSAQVAG LCGRLTLHRD LRTGRWEPDP QRSRRCLRDP QRVLEYCRQM YPELQIARVE QATQAIPMER WCGGSRSGSC AHPHHQVVPF RCLPGEFVSE ALLVPEGCRF LHQERMDQCE SSTRRHQEAQ EACSSQGLIL HGSGMLLPCG SDRFRGVEYV CCPPPGTPDP SGTAVGDPST RSWPPGSRVE GAEDEEEEES FPQPVDDYFV EPPQAEEEEE TVPPPSSHTL AVVGKVTPTP RPTDGVDIYF GMPGEISEHE GFLRAKMDLE ERRMRQINEV MREWAMADNQ SKNLPKADRQ ALNEHFQSIL QTLEEQVSGE RQRLVETHAT RVIALINDQR RAALEGFLAA LQADPPQAER VLLALRRYLR AEQKEQRHTL RHYQHVAAVD PEKAQQMRFQ VHTHLQVIEE RVNQSLGLLD QNPHLAQELR PQIQELLHSE HLGPSELEAP APGGSSEDKG GLQPPDSKDD TPMTLPKGST EQDAASPEKE KMNPLEQYER KVNASVPRGF PFHSSEIQRD ELAPAGTGVS RE
- 特异性
- Ser39-Glu580
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <0.1EU/μg
- Top Product
- Discover our top product APLP1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
- 别名
- APLP-1 (APLP1 产品)
- 别名
- aplp Protein, MGC115336 Protein, APLP Protein, Aplp1_retired Protein, RGD1561211 Protein, amyloid beta precursor like protein 1 Protein, amyloid beta precursor like protein 1 L homeolog Protein, amyloid beta (A4) precursor-like protein 1 Protein, APLP1 Protein, aplp1.L Protein, aplp1 Protein, Aplp1 Protein
- 背景
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Description: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
Name: APLP1,APLP
- 基因ID
- 333
- UniProt
- P51693
- 途径
- cAMP Metabolic Process
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