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APLP1 Protein (His tag)

APLP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7535312
发货至: 中国
  • 抗原 See all APLP1 蛋白
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 4
    资源
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This APLP1 protein is labelled with His tag.
    原理
    Recombinant Human APLP-1 Protein
    序列
    SLAGGSPGAA EAPGSAQVAG LCGRLTLHRD LRTGRWEPDP QRSRRCLRDP QRVLEYCRQM YPELQIARVE QATQAIPMER WCGGSRSGSC AHPHHQVVPF RCLPGEFVSE ALLVPEGCRF LHQERMDQCE SSTRRHQEAQ EACSSQGLIL HGSGMLLPCG SDRFRGVEYV CCPPPGTPDP SGTAVGDPST RSWPPGSRVE GAEDEEEEES FPQPVDDYFV EPPQAEEEEE TVPPPSSHTL AVVGKVTPTP RPTDGVDIYF GMPGEISEHE GFLRAKMDLE ERRMRQINEV MREWAMADNQ SKNLPKADRQ ALNEHFQSIL QTLEEQVSGE RQRLVETHAT RVIALINDQR RAALEGFLAA LQADPPQAER VLLALRRYLR AEQKEQRHTL RHYQHVAAVD PEKAQQMRFQ VHTHLQVIEE RVNQSLGLLD QNPHLAQELR PQIQELLHSE HLGPSELEAP APGGSSEDKG GLQPPDSKDD TPMTLPKGST EQDAASPEKE KMNPLEQYER KVNASVPRGF PFHSSEIQRD ELAPAGTGVS RE
    特异性
    Ser39-Glu580
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Top Product
    Discover our top product APLP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    别名
    APLP-1 (APLP1 产品)
    别名
    aplp Protein, MGC115336 Protein, APLP Protein, Aplp1_retired Protein, RGD1561211 Protein, amyloid beta precursor like protein 1 Protein, amyloid beta precursor like protein 1 L homeolog Protein, amyloid beta (A4) precursor-like protein 1 Protein, APLP1 Protein, aplp1.L Protein, aplp1 Protein, Aplp1 Protein
    背景

    Description: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

    Name: APLP1,APLP

    基因ID
    333
    UniProt
    P51693
    途径
    cAMP Metabolic Process
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