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TGFBR1 Protein (AA 311-501) (His tag)

TGFBR1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505539
发货至: 中国
  • 抗原 See all TGFBR1 蛋白
    TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
    蛋白类型
    Recombinant
    产品特性
    AA 311-501
    宿主
    • 15
    • 4
    • 2
    • 1
    大鼠
    资源
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TGFBR1 protein is labelled with His tag.
    序列
    Leu 311-Met 501
    产品特性
    A DNA sequence encoding the Rat TGFBR1 protein (P80204) (Leu 311-Met 501) was expressed with N-His tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product TGFBR1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
    别名
    TGFBR1 (TGFBR1 产品)
    背景

    Abbreviation: TGFBR1

    Target Synonym: AAT5,Activin receptor like kinase 5,ACVRLK4,ALK-5,LDS1A,LDS2A,MSSE,SKR4,TbetaR I,TGF-beta receptor type-1,TGFBR1,Transforming growth factor beta receptor 1

    Background: Most cell types express three sizes of receptors for TGF-beta. These are designated Type I (53 kDa), Type II (70-85 kDa), and Type III (250-350 kDa). The Type III receptor, a proteoglycan that exists in membrane-bound and soluble forms, binds TGF-beta 1, TGF-beta 2, and TGF-beta 3 but does not appear to be involved in signal transduction. The Type II receptor is a membrane-bound serine/threonine kinase that binds TGF-beta 1 and TGF-beta 3 with high affinity and TGF-beta 2 with a much lower affinity. The Type I receptor, originally known as ALK-5 (Activin receptor?like kinase) is also a membrane-bound serine/threonine kinase that apparently requires the presence of the Type II receptor to bind TGF-beta. Current evidence suggests that signal transduction requires the cytoplasmic domains of both the Type I and Type II receptors.

    分子量

    Calculated MW: 20.9 kDa

    Observed MW: 28 kDa

    UniProt
    P80204
    途径
    Growth Factor Binding
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