S100A8 Protein (AA 2-89) (His tag)
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- 抗原 See all S100A8 蛋白
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-89
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This S100A8 protein is labelled with His tag.
- 序列
- Pro2-Glu89
- 产品特性
- A DNA sequence encoding the Mouse S100a8 protein(P27005) (2P-89G) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- >90 % as determined by reducing SDS-PAGE.
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- Discover our top product S100A8 蛋白
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S100 Calcium Binding Protein A8 (S100A8) (AA 1-93) protein (His tag)
S100A8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
S100 Calcium Binding Protein A8 (S100A8) (AA 1-93) protein (GST tag)S100A8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
S100 Calcium Binding Protein A8 (S100A8) (AA 2-89) protein (His tag)S100A8 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
S100 Calcium Binding Protein A8 (S100A8) (AA 1-92) protein (GST tag)S100A8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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used as Immunogen for (ABIN6999927, ABIN7234313, ABIN7234314 and ABIN7234315)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- 别名
- S100a8 (S100A8 产品)
- 别名
- 60B8AG Protein, CAGA Protein, CFAG Protein, CGLA Protein, CP-10 Protein, L1Ag Protein, MA387 Protein, MIF Protein, MRP8 Protein, NIF Protein, P8 Protein, Mrp8 Protein, S100A8 Protein, 60B8Ag Protein, AI323541 Protein, B8Ag Protein, CFAg Protein, Caga Protein, p8 Protein, MRP-8 Protein, S100 calcium binding protein A8 Protein, S100 calcium binding protein A8 (calgranulin A) Protein, S100A8 Protein, S100a8 Protein
- 背景
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Background: S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2/P67PHOX. The extracellular functions involve proinflammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration.
Synonym: 60B8AG, CAGA, Calgranulin A, Calprotectin L1L subunit, CFAG, CGLA, CP 10, Cystic fibrosis antigen, L1Ag, MA387, MIF, MRP-8, MRP8, NIF, P8, Protein S100-A8, S100A8, Urinary stone protein band A,Pro-inflammatory S100 cytokine,S100 calcium-binding protein A8
- 分子量
- 11.5 kDa
- UniProt
- P27005
- 途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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