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GSTM1 Protein (AA 2-218) (His tag)

GSTM1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505356
发货至: 中国
  • 抗原 See all GSTM1 蛋白
    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
    蛋白类型
    Recombinant
    产品特性
    AA 2-218
    宿主
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 11
    • 5
    • 2
    大肠杆菌(E. Coli)
    标记
    This GSTM1 protein is labelled with His tag.
    序列
    Pro2-Lys218
    产品特性
    A DNA sequence encoding the Mouse Gstm1 (P10649-1) (Pro2-Lys218) was expressed with a polyhistidine tag at the N-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product GSTM1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
    别名
    GSTM1 (GSTM1 产品)
    别名
    GST1 Protein, GSTM1-1 Protein, GSTM1a-1a Protein, GSTM1b-1b Protein, GTH4 Protein, GTM1 Protein, H-B Protein, MU Protein, MU-1 Protein, GSTA3 Protein, Gstb-1 Protein, Gstb1 Protein, gst-mu Protein, gst1 Protein, gstm1 Protein, gstm2 Protein, gth4 Protein, gtm1 Protein, glutathione S-transferase mu 1 Protein, glutathione S-transferase M1 Protein, glutathione S-transferase, mu 1 Protein, glutathione S-transferase Mu 1 Protein, glutathione S-transferase mu 2 (muscle) Protein, glutathione S-transferase mu 1 L homeolog Protein, GSTM1 Protein, Gstm1 Protein, LOC100356307 Protein, GSTM2 Protein, LOC100731426 Protein, gstm1.L Protein
    背景

    Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

    Synonym: Glutathione S-transferase Mu 1,GST class-mu 1,GST HB subunit 4,GST1,Gstm1,GSTM1-1,GSTM1,GSTM1a-1a,GSTM1b-1b,GTH4,GTM1,H-B,LIVER AND FIBROBLAST GST1,MU,MU-1

    分子量
    25.7 kDa
    途径
    Negative Regulation of Transporter Activity
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