Ki-67 Protein (AA 1001-1112) (His tag)
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- 抗原 See all Ki-67 (MKI67) 蛋白
- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1001-1112
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Ki-67 protein is labelled with His tag.
- 序列
- Lys1001-Pro1112
- 产品特性
- A DNA sequence encoding theHuman KI67 protein (P46013) (Lys1001-Pro1112) was expressed with a N-His.
- 纯度
- >85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MKI67 蛋白
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Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 762-1016) protein (His tag)
MKI67 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 3157-3256) protein (GST tag)MKI67 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
- 别名
- KI67 (MKI67 产品)
- 别名
- MKI67 Protein, kia Protein, mki67 Protein, MGC132156 Protein, D630048A14Rik Protein, Ki-67 Protein, Ki67 Protein, KIA Protein, MIB-1 Protein, marker of proliferation Ki-67 Protein, marker of proliferation Ki-67 L homeolog Protein, marker of proliferation Ki-67 S homeolog Protein, antigen identified by monoclonal antibody Ki 67 Protein, antigen identified by monoclonal antibody Ki-67 Protein, nucleolar protein interacting with the FHA domain of MKI67 Protein, MKI67 Protein, mki67 Protein, mki67.L Protein, mki67.S Protein, Mki67 Protein, NIFK Protein
- 背景
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Background: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly.Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface.Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility.Binds DNA, with a preference for supercoiled DNA and AT-rich DNA.Does not contribute to the internal structure of mitotic chromosomes.May play a role in chromatin organization.It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
Synonym: Antigen identified by monoclonal antibody Ki-67,Antigen KI-67,Antigen Ki67
- 分子量
- 12.4 kDa
- UniProt
- P46013
- 途径
- Glycosaminoglycan Metabolic Process
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