Claudin 1 Protein (CLDN1) (AA 29-115) (His tag)
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- 抗原 See all Claudin 1 (CLDN1) 蛋白
- Claudin 1 (CLDN1)
- 蛋白类型
- Recombinant
- 产品特性
- AA 29-115
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Claudin 1 protein is labelled with His tag.
- 序列
- Gln29-Lys115
- 产品特性
- A DNA sequence encoding theHuman CLDN1 protein (O95832) (Gln29-Lys115) was expressed with a N-His.
- 纯度
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CLDN1 蛋白
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Claudin 1 (CLDN1) (AA 1-211) protein (GST tag)
CLDN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Claudin 1 (CLDN1) (AA 1-211) protein (Strep Tag)Crystallography grade CLDN1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Claudin 1 (CLDN1) (AA 1-211) protein (Strep Tag)Crystallography grade CLDN1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Claudin 1 (CLDN1) protein (Myc-DYKDDDDK Tag)CLDN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Claudin 1 (CLDN1)
- 别名
- CLDN1 (CLDN1 产品)
- 别名
- CLD1 Protein, ILVASC Protein, SEMP1 Protein, AI596271 Protein, cldn19 Protein, claudin-1 Protein, cld1 Protein, ilvasc Protein, semp1 Protein, CLDN1 Protein, claudin 1 Protein, claudin 1 S homeolog Protein, CLDN1 Protein, Cldn1 Protein, cldn1 Protein, cldn1.S Protein
- 背景
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Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
Synonym: Senescence-associated epithelial membrane protein
- 分子量
- 9.6 kDa
- UniProt
- O95832
- 途径
- Cell-Cell Junction Organization, Hepatitis C
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