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GAPDH Protein (AA 1-333) (His tag)

GAPDH 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7504953
发货至: 中国
  • 抗原 See all GAPDH 蛋白
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    蛋白类型
    Recombinant
    产品特性
    AA 1-333
    宿主
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    资源
    • 38
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    大肠杆菌(E. Coli)
    标记
    This GAPDH protein is labelled with His tag.
    序列
    Met1-Glu333
    产品特性
    A DNA sequence encoding the Human GAPDH (P04406) (1M-333E) was expressed with a polyhistidine tag at the N-terminus.
    纯度
    >90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product GAPDH 蛋白
  • 说明

    used as Immunogen for (ABIN6999908, ABIN7234256, ABIN7234257 and ABIN7234258)

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    别名
    GAPDH (GAPDH 产品)
    别名
    G3PD Protein, GAPD Protein, Gapd Protein, BEST:GH12586 Protein, CG12055 Protein, Dmel\\CG12055 Protein, GA3PDH Protein, GADPH Protein, GAP Protein, GAPDH Protein, GAPDH I Protein, GAPDH-1 Protein, GAPDH1 Protein, GAPDHI Protein, Gapdh Protein, Gapdh-1 Protein, Gapdh43E Protein, gadph Protein, gapdh Protein, gapdh-1 Protein, gh12586 Protein, cb609 Protein, gapd Protein, mg:bb02e05 Protein, wu:fb33a10 Protein, wu:ft80f05 Protein, KNC-NDS6 Protein, g3pd Protein, G3PDH Protein, glyceraldehyde-3-phosphate dehydrogenase Protein, Glyceraldehyde 3 phosphate dehydrogenase 1 Protein, glyceraldehyde-3-phosphate dehydrogenase S homeolog Protein, glyceraldehyde-3-phosphate dehydrogenase, type I Protein, olfactory receptor 8K3 Protein, GAPDH Protein, Gapdh Protein, Gapdh1 Protein, gapdh Protein, gapdh.S Protein, gapDH Protein, LOC100404960 Protein, LOC614985 Protein
    背景

    Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

    Synonym: Aging associated gene 9 protein,Epididymis secretory sperm binding protein Li 162eP,G3P,G3PD,G3PDH,GAPD,GAPDH,Glyceraldehyde 3 phosphate dehydrogenase,Glyceraldehyde-3-phosphate dehydrogenase,HEL S 162eP,Peptidyl-cysteine S-nitrosylase GAPDH

    分子量
    37.1 kDa
    UniProt
    P04406
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