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Oncostatin M Receptor Protein (OSMR) (AA 28-740) (Fc Tag)

OSMR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7504493
发货至: 中国
  • 抗原 See all Oncostatin M Receptor (OSMR) 蛋白
    Oncostatin M Receptor (OSMR)
    蛋白类型
    Recombinant
    产品特性
    AA 28-740
    宿主
    • 14
    • 6
    • 2
    • 1
    • 1
    资源
    • 10
    • 6
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This Oncostatin M Receptor protein is labelled with Fc Tag.
    原理
    Human OSMR Protein
    序列
    Glu28-Met740
    产品特性
    Recombinant Human OSMR Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Glu28-Met740.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product OSMR 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Oncostatin M Receptor (OSMR)
    别名
    OSMR (OSMR 产品)
    别名
    OSMRB Protein, PLCA1 Protein, oncostatin M receptor Protein, OSMR Protein, Osmr Protein
    背景
    OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
    分子量
    107.06 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling, Growth Factor Binding
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