Recombinant Human HLA-A*03:01 & B2M & KRAS G12V (VVGAVGVGK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-TerminusIt contains Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and VVGAVGVGK peptide.
纯度
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
储存条件
-80 °C
储存方法
Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
有效期
12 months
抗原
HLA-A*03:01
背景
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
分子量
50.09 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Tris-Bis PAGE result.