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APCDD1 Protein (AA 27-492)

APCDD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7504233
发货至: 中国
  • 抗原 See all APCDD1 蛋白
    APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))
    蛋白类型
    Recombinant
    产品特性
    AA 27-492
    宿主
    • 7
    • 3
    • 1
    • 1
    资源
    • 4
    • 4
    • 2
    • 2
    HEK-293 Cells
    原理
    Human APCDD1 Protein
    序列
    Leu27-His492
    产品特性
    Recombinant Human APCDD1 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Leu27-His492.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product APCDD1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))
    别名
    APCDD1 (APCDD1 产品)
    别名
    drapc1 Protein, xPgo Protein, APCDD1 Protein, Pgo1 Protein, cAPCDD1 Protein, B7323 Protein, DRAPC1 Protein, HHS Protein, HTS Protein, AB023957 Protein, AU041258 Protein, Drapc1 Protein, EIG180 Protein, adenomatosis polyposis coli down-regulated 1 Protein, APC down-regulated 1 Protein, adenomatosis polyposis coli down-regulated 1 L homeolog Protein, apcdd1 Protein, APCDD1 Protein, Apcdd1 Protein, apcdd1.L Protein
    背景
    Adenomatosis polyposis coli downregulated 1 (APCDD1), a negative regulator of Wnt signaling, was examined to understand detailed mechanisms underlying Wnt signaling tooth development. In situ hybridization showed that Apcdd1 was expressed in the condensed mesenchyme at the bud stage, and in the inner enamel epithelium (IEE), including enamel knot (EK) at the cap stage. APCDD1 modulates the gene expression of Wnt- and EK-related signaling molecules at the cap stage of tooth development, and is involved in tooth cusp patterning by modulating the epithelial rearrangement in the IEE.
    分子量
    80.06 kDa. Due to glycosylation, the protein migrates to 82-110 kDa based on Tris-Bis PAGE result.
    UniProt
    Q8J025
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