CTXB Protein (His tag)
MALS verified
CTXB
宿主: Vibrio sp.
宿主: HEK-293 Cells
Recombinant
95 %
-
- 抗原 See all CTXB products
- CTXB (CtxB Gene Product (CTXB))
- 蛋白类型
- Recombinant
- 宿主
- Vibrio sp.
- 资源
- HEK-293 Cells
- 标记
- This CTXB protein is labelled with His tag.
- 原理
- Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Cholera enterotoxin subunit B Protein, His Tag (MALS verified)
- 序列
- Thr 22 - Asn 124
- 产品特性
- Vibrio cholerae serotype O1 Cholera enterotoxin subunit B, His Tag is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Asn 124 (Accession # P01556).
- 纯度
- 95 %
- 内毒素水平
- 1.0 EU per μg
- 质量等级
- MALS verified
-
- 说明
-
This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 13.5 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
-
- 抗原
- CTXB (CtxB Gene Product (CTXB))
- 别名
- Cholera Enterotoxin Subunit B (CTXB 产品)
- 背景
- Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge.
- 分子量
- 13.5 kDa
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