ADAM9 Protein (His tag)
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- 抗原 See all ADAM9 蛋白
- ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This ADAM9 protein is labelled with His tag.
- 原理
- Mouse ADAM9 Protein, His Tag (active enzyme, MALS verified)
- 序列
- Ala 206 - Asp 697
- 产品特性
- Mouse ADAM9, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 206 - Asp 697 (Accession # Q61072).
- 纯度
- 95 %
- 内毒素水平
- 1.0 EU per μg
- 质量等级
- MALS verified
- Top Product
- Discover our top product ADAM9 蛋白
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ADAM Metallopeptidase Domain 9 (ADAM9) (AA 29-697) protein (His tag)
ADAM9 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
ADAM Metallopeptidase Domain 9 (ADAM9) (AA 36-135) protein (GST tag)ADAM9 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 55.2 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 25 mM MES,150 mM NaCl, pH 6.0
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))
- 别名
- ADAM9 (ADAM9 产品)
- 别名
- CORD9 Protein, MCMP Protein, MDC9 Protein, Mltng Protein, AU020942 Protein, mKIAA0021 Protein, adam9-A Protein, cord9 Protein, mcmp Protein, mltng Protein, Adam9 Protein, zgc:101824 Protein, ADAM9 Protein, ADAM metallopeptidase domain 9 Protein, a disintegrin and metallopeptidase domain 9 (meltrin gamma) Protein, ADAM metallopeptidase domain 9 L homeolog Protein, ADAM9 Protein, Adam9 Protein, adam9.L Protein, adam9 Protein
- 背景
- ADAM9 (A disintegrin and a metalloprotease 9) is a membrane-anchored protein that participates in a variety of physiological functions, primarily through the disintegrin domain for adhesion and the metalloprotease domain for ectodomain shedding of a wide variety of cell surface proteins. ADAM9 influences the developmental process, inflammation, and degenerative diseases.Recently, increasing evidence has shown that ADAM9 plays an important role in tumor biology. Overexpression of ADAM9 has been found in several cancer types and is correlated with tumoraggressiveness and poor prognosis. In addition, through either proteolytic or non-proteolytic pathways, ADAM9 promotes tumor progression, therapeutic resistance, and metastasis of cancers.Therefore, comprehensively understanding the mechanism of ADAM9 is crucial for the development of therapeutic anti-cancer strategies. In this review, we summarize the current understanding of ADAM9 in biological function, pathophysiological diseases, and various cancers. Recent advances in therapeutic strategies using ADAM9-related pathways are presented as well.
- 分子量
- 55.2 kDa
- 途径
- Cellular Response to Molecule of Bacterial Origin, SARS-CoV-2 Protein Interactome
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