Claudin 6 Protein (CLDN6) (His tag,Twin-Strep tag)
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- 抗原 See all Claudin 6 (CLDN6) 蛋白
- Claudin 6 (CLDN6)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Insect Cells
- 标记
- This Claudin 6 protein is labelled with His tag,Twin-Strep tag.
- 原理
- Human Claudin-6 / CLDN6 Protein, His,Twin-Strep Tag (Detergent)
- 序列
- Ala 2 - Val 220
- 产品特性
- Human Claudin-6 Protein, His,Twin-Strep Tag is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Val 220 (Accession # P56747-1).
- 纯度
- 80 %
- 内毒素水平
- 1.0 EU per μg
- Top Product
- Discover our top product CLDN6 蛋白
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- 说明
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This protein carries a polyhistidine tag at the N-terminus and a twin strep tag at the C-terminus. (10xHis , Twin-Strep) The protein has a calculated MW of 28.3 kDa. The protein migrates as 26-27 kDa under reducing (R) condition (SDS-PAGE).
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- Claudin 6 (CLDN6)
- 别名
- Claudin-6 (CLDN6 产品)
- 别名
- cldn4l2 Protein, cldn6 Protein, CLDN6 Protein, AL024037 Protein, claudin 6, gene 1 L homeolog Protein, claudin 6 Protein, cldn6.1.L Protein, CLDN6 Protein, Cldn6 Protein
- 背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin-6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16.
- 分子量
- 28.3 kDa
- 途径
- Hepatitis C
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