Muscarinic Acetylcholine Receptor M2 蛋白
CHRM2
宿主: 人
宿主: HEK-293 Cells
Synthetic
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- 抗原 See all Muscarinic Acetylcholine Receptor M2 (CHRM2) 蛋白
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- 蛋白类型
- Synthetic
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CHRM2 full length protein-synthetic nanodisc
- 产品特性
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CHRM2 蛋白
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Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 251-350) protein (GST tag)
CHRM2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 应用备注
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- 说明
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- 别名
- CHRM2 (CHRM2 产品)
- 别名
- HM2 Protein, AChR-M2 Protein, Chrm-2 Protein, M2 Protein, chrm2 Protein, Acm2 Protein, GPM2 Protein, cholinergic receptor muscarinic 2 Protein, cholinergic receptor, muscarinic 2, cardiac Protein, cholinergic receptor, muscarinic 2a Protein, cholinergic receptor, muscarinic 2 Protein, CHRM2 Protein, Chrm2 Protein, chrm2a Protein
- 背景
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HM2
Description: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] - 分子量
- The human full length CHRM2 protein has a MW of 51.5 kDa
- UniProt
- P08172
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