MRGPRX2 蛋白
MRGPRX2
宿主: 人
宿主: HEK-293 Cells
Synthetic
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- 抗原 See all MRGPRX2 蛋白
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
- 蛋白类型
- Synthetic
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human MRGPRX2 full length protein-synthetic nanodisc
- 产品特性
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product MRGPRX2 蛋白
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G Protein-Coupled Receptor MRGX2 (MRGPRX2) (AA 1-330) protein (GST tag)
MRGPRX2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 应用备注
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- 说明
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
- 别名
- MRGPRX2 (MRGPRX2 产品)
- 别名
- MRGX2 Protein, G370024M05Rik Protein, MrgB10 Protein, Mrgprb10 Protein, MrgB1 Protein, Mrgprb1 Protein, MAS related GPR family member X2 Protein, MAS-related GPR, member X2 Protein, MRGPRX2 Protein, Mrgprx2 Protein
- 背景
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MGRG3, MRGX2
Description: Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.[UniProtKB/Swiss-Prot Function] - 分子量
- The human full length MRGPRX2 protein has a MW of 37.1 kDa
- UniProt
- Q96LB1
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