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CCR9 蛋白

CCR9 宿主: 人 宿主: HEK-293 Cells Synthetic
产品编号 ABIN7491572
发货至: 中国
  • 抗原 See all CCR9 蛋白
    CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))
    蛋白类型
    Synthetic
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    原理
    Human CCR9 full length protein-synthetic nanodisc
    产品特性
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product CCR9 蛋白
  • 应用备注
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    说明

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))
    别名
    CCR9 (CCR9 产品)
    别名
    CC-CKR-9 Protein, CDw199 Protein, GPR-9-6 Protein, GPR28 Protein, A130091K22Rik Protein, Cmkbr10 Protein, C-C motif chemokine receptor 9 Protein, chemokine (C-C motif) receptor 9 Protein, CCR9 Protein, Ccr9 Protein
    背景
    CC-CKR-9, CDw199, GPR-9-6, GPR28
    Description: The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
    分子量
    The human full length CCR9 protein has a MW of 42.02 kDa
    UniProt
    P51686
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