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TSH receptor 蛋白

TSHR 宿主: 人 宿主: HEK-293 Cells Synthetic
产品编号 ABIN7491755
发货至: 中国
  • 抗原 See all TSH receptor (TSHR) 蛋白
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    蛋白类型
    Synthetic
    宿主
    • 6
    • 2
    • 1
    资源
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    原理
    Human TSHR full length protein-synthetic nanodisc
    产品特性
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product TSHR 蛋白
  • 应用备注
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    说明

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    别名
    TSHR (TSHR 产品)
    别名
    CHNG1 Protein, LGR3 Protein, hTSHR-I Protein, AI481368 Protein, hypothroid Protein, hyt Protein, pet Protein, TSHRA Protein, TSH-R Protein, thyroid stimulating hormone receptor Protein, tshr Protein, TSHR Protein, Tshr Protein
    背景
    CHNG1, hTSHR-I, LGR3
    Description: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
    分子量
    The human full length TSHR protein has a MW of 86.83 kDa
    UniProt
    P16473
    途径
    Thyroid Hormone Synthesis
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